Non-Small Cell Lung Cancer Prognosis Based In A Cut-Off Value For Plasma Basic Fibroblast Growth Factor Expression

Background: Angiogenesis is regulated by angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) that may be deregulated in lung cancer. The aim of this study was to find out a pattern of VEGF and bFGF protein expression in exhaled breath condensate (EBC) and serum of non-small cell lung cancer (NSCLC) patients and healthy volunteers (smokers and nonsmokers) to obtain early diagnostic values to discriminate initial stages of disease.