Key result
The LACE index demonstrated poor discrimination for predicting 30-day readmissions in older UK inpatients (c-statistic 0.55), suggesting routine screening may not be cost-effective.
Why the study?
Is screening and intervening to prevent hospital readmissions in older people cost-effective?
Is screening and intervening to prevent hospital readmissions in older people cost-effective?
Effect estimate: c-statistic 0.55
Screening older patients to prevent hospital readmissions is unlikely to be cost-effective, highlighting the need for improved in-patient comprehensive geriatric assessment and integrated care pathways instead.
Heath services throughout the world are facing challenging times—the global recession and the ageing population are conspiring to produce a perfect storm, in which much more gain is required from significantly less resource. Older people are major users of hospital services, and once admitted to hospital, are at high risk of adverse events [1,2], have long stays, high readmission rates and high rates of long-term care use [3]. A major focus of health policy in England and Wales is how to reduce readmissions following an episode of acute care; there has been an increase the funding tariff paid for an acute episode of care, but with hospitals is being financially disadvantaged for patients being readmitted within 30 days. In conjunction with the changes in tariff, non-recurrent funding has been set aside to develop community services aimed at reducing the risk of readmission; 14% of patients aged over 75 were readmitted within 30 days in England during 2008 [4]. It is estimated that patients readmitted within a month of discharge cost the NHS £2.6 billion each year [5]. The reasons for readmissions in older people are not well understood, but are often due to a complex interplay between physical and mental health issues as well as factors such as the availability of carers. This is played out over the fragile interface between primary and secondary care, with the associated challenge of delivering timely, accurate and comprehensive communication. The system factors and policy drivers make the concept of identifying people at a high risk of readmission with the aim of intervening to prevent readmissions appear an attractive proposition. In the current issue of Age and Ageing, Cotter et al. report on the use of the LACE index in the UK population. The LACE index (L, length of stay; A, Admission type; C, Co-morbidity; E, ED attendances) has previously been validated in a Canadian population for predicting readmission and death following discharge, but excluded patients with cognitive impairment or those who lived in care homes. Cotter et al. tested the LACE score on 507 randomly selected older patients with a variety of comorbidities. At 30 days, 90 (17.8%) were readmitted and 23 (4.5%) had died; the c-statistic was 0.55 and 0.70, respectively. Cotter et al. concluded that the LACE index is a poor tool for predicting 30 day readmissions in older UK inpatients and suggested that more detailed patient level information is required to improve the performance of readmission prediction tools. A recent systemic review by Kansagara et al. [6] of 26 tools to predict readmission showed none to be particularly useful. Even if people are identified as being at risk of readmission there is a discussion to be had about the interventions that might be implemented to reduce this risk. Structured, multidisciplinary post-discharge support visits have been shown to reduce readmissions in patients with heart failure [7–14], COPD [15, 16] and frail older people more generally [14, 17–22]. The addition of telemonitoring appears to be additionally effective in patients with heart failure [23–26], as does improved self-management for people with long-term conditions [27]. However, the concept of adding in additional services to address readmission risk may be flawed. Even if we had a screening tool with near perfect properties (sensitivity and specificity at 90% each), an additional service is unlikely to ever be cost-effective. Consider a population of 500 older people being discharged from hospital with a readmission rate of 15%; using the perfect screening tool, the numbers identified for intervention are shown in Table 1. Modelling screening and intervening for hospital readmissions Modelling screening and intervening for hospital readmissions Overall the most likely impact of a service aimed at preventing readmissions is a 6–7% reduction in readmissions (based on trials of CGA over the interface (Stuck et al. [28], Baztan et al. [29], Hyde et al. [30])). In the most optimistic of scenarios where the ‘readmission service’ prevented 10% of readmissions and cost only £100 per patient, it would see 110 patients, costing £11,000 and might prevent seven admissions (68*10%). If a readmission cost £1500 (generous), then the service would lose £500 (£11,000 cost minus £10,500 in readmissions prevented). As it is screening tools are nowhere near this accurate, and it is unlikely that any effective intervention would cost as little as £100 (this amounts to a few hours of nurse or therapy input). It is possible to model a variety of scenarios using the above logic, none of which suggest that screening and intervening for readmission is likely to be cost-effective. And given the economic climate, if is not cost-effective, then we should not be doing it. So what should we be doing about readmissions if screening and intervening around the time of discharge to prevent readmissions is unlikely to be affordable? Perhaps the best hope comes from an Australian study which highlighted the impact of CGA for in-patients combined with on-going community support—a vertical integrated care pathway for older people. This intervention reduced readmissions by half [31] and appeared to be cost-effective (net-monetary-benefit per individual for the intervention group compared with the usual care condition was AUS$7,907 [32]). Efforts to reduce readmissions should focus on improving in-patient management, ensuring that frail older people with acute care needs receive CGA and developing better and inexpensive methods of linking with existing primary care and social services to enhance communication at the time of discharge.
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Conroy et al. (2012) conducted an editorial in Hospital readmission (n=507). LACE index was evaluated on 30-day readmission (c-statistic 0.55). The LACE index demonstrated poor discrimination for predicting 30-day readmissions in older UK inpatients (c-statistic 0.55), suggesting routine screening may not be cost-effective.
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