Key result
In children with idiopathic ventricular arrhythmias, localization of the ectopic focus in the right ventricular free wall was associated with a significantly lower left ventricular ejection fraction compared to the right ventricular outflow tract (63.4% vs 65.8%, p<0.01).
Why the study?
To determine the prevalence of ventricular arrhythmias among children with cardiac arrhythmias and assess clinical, functional, and electrophysiological characteristics based on ectopic focus localization.
Population
260 children with ventricular arrhythmias
Comparison
Clinical and functional characteristics compared across ectopic focus localizations
Design
Observational comparative study
Authors
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Observational pediatric VA data warrant cautious use in risk assessment; leaves open need for prospective outcome studies by focus site.
Observational (n=260)
No
Absolute Event Rate: 63.4% vs 65.8%
p-value: p=<0.01
In children with idiopathic ventricular arrhythmias, the right ventricular outflow tract is the most common ectopic focus, while localization in the right ventricular free wall is associated with slightly lower left ventricular ejection fraction and higher rates of polymorphic complexes.
Olga Yeliseyeva (2021) conducted an observational in Idiopathic ventricular arrhythmias (n=260). Ectopic focus localization in the right ventricular free wall vs. Ectopic focus localization in the right ventricular outflow tract (RVOT) was evaluated on Left ventricular ejection fraction on sinus rhythm (p=<0.01). In children with idiopathic ventricular arrhythmias, localization of the ectopic focus in the right ventricular free wall was associated with a significantly lower left ventricular ejection fraction compared to the right ventricular outflow tract (63.4% vs 65.8%, p<0.01).
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