Multiple mechanisms of successful slow-pathway catheter ablation of common atrioventricular nodal re-entrant tachycardia
Why the study?
Does slow-pathway catheter ablation cause specific electrophysiological modifications of atrioventricular nodal conducting properties in patients with atrioventricular nodal re-entrant tachycardia?
Population
104 patients affected by the common form of atrioventricular nodal re-entrant tachycardia
Comparison
Catheter ablation of the slow pathway vs Pre-ablation baseline
Design
Cohort
Authors
Discussion
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Member takes
Implication
Ablation success in AVNRT occurs across heterogeneous AV nodal modifications; leaves open prospective validation of age and site-specific effects.
Structured PICO
Does slow-pathway catheter ablation cause specific electrophysiological modifications of atrioventricular nodal conducting properties in patients with atrioventricular nodal re-entrant tachycardia?
P
Population
104 patients affected by the common form of atrioventricular nodal re-entrant tachycardia (mean age 52 +/- 16 years; 69 women)
I
Intervention
Catheter ablation of the slow pathway
C
Comparator
Pre-ablation baseline (before and after comparison)
O
Outcome
Modifications of the antegrade atrioventricular nodal function curvesurrogate
Successful ablation of AVNRT results in heterogeneous modifications of antegrade AV conduction, suggesting success depends on critical tissue damage at various sites rather than a single specific electrophysiological change, and is influenced by patient age.
Cite This Study
Brignole et al. (1997) studied this question.