Amphotericin B: delivery systems

Because the clinical utility of amphotericin B (AmB) is limited by its toxicity of host cells, an important question is how to best direct it specifically to the fungus or at least to the site of infection or, alternatively, how to keep it away from the host cells. One strategy is to use a vehicle other than deoxycholate. In this minireview, we review some of the relevant studies addressing this issue