Non-Beta-Blocker Medications with Beta-Blocker Like Properties: A Systematic Review of Side Effects.

Background: beta-blockers have been used several times to treat various cardiovascular and non-cardiovascular diseases. However, there is some time limited by side effects and contraindications. Recently, several studies suggest that several medications (not belonging to beta-blocker classes) may have a beta-blocking impact or bind to beta receptors. Aim: This is a systemic review conducted to find out the non-Beta blocker medications that have a degree of beta-blocking effect. Materials and Methods: This systemic review was conducted by using search engines; we found about 1090 articles related to our aim using search Keywords such as "beta blocker", "bronchospasm", and "increase peripheral vascular resistance" on several search engines, including PubMed, Google Scholar, Base search, in articles published from 2010 to march 2023. Result: the review focused on the adverse effects of several medications on several classes and identified several non-beta blocker medications that may have Beta-blocker effects as side effects such as bradycardia, bronchospasm, Raynaud syndromes, and increased blood resistance. Conclusion: Understanding the beta-blocking side effects of several not beta blocker medications may open the field of understanding the mechanisms of action of this medication or this medication may really bond to beta receptors and produce these effects.