We describe a new seven-stage synthesis of the carbazole alkaloids hyellazole and 6-chlorohyellazole, which proceeds via thermal cyclization of the 3-(buta-1,3-dienyl)indoles 7ab and 7bb, prepared from the condensation products of indole-2,3-diones 1a, b and the 3-methyl-4-phenylbut-3-en-2-one 2b. This procedure was also used to prepare related 3-methoxy-1-phenylcarbazole derivatives.
No takes yet. Share an insight, caveat, or question.
Beccalli et al. (1994) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: