Key result
Older age is linked to ~33% higher risk of incident prediabetes.
Why the study?
What are the risk factors associated with the incidence of prediabetes in adults in Bogor, Indonesia?
Cohort
What are the risk factors associated with the incidence of prediabetes in adults in Bogor, Indonesia?
Answers are grounded in this paper and cite their sources.
In an Indonesian cohort, over half of adults developed prediabetes, with age, female gender, obesity, hypertension, and high cholesterol identified as significant risk factors.
Background: Prediabetes is a golden period because the blood sugar levels can be lowered to normal levels, unlike diabetes mellitus. Studies on risk factors of prediabetes in Indonesia have never been conducted before, especially with cohort study design. The purpose of this study was to identify risk factors associated with prediabetes in Indonesia based on a cohort study conducted in Bogor, Indonesia. Study Design: A retrospective cohort study. Methods: This study was conducted using data from the Bogor Cohort Study done by the Ministry of Health of Indonesia, which included individuals aged more than 25 years. Individuals who had impaired fasting glucose (IFG) (100-125 mg/dL) and/or impaired glucose tolerance (IGT) (140-199 mg/dL) at baseline screening were excluded from the study. Demographic characteristics, risk factors, and clinical observations were extracted using a questionnaire. Cox regression was used for data analysis. Results: The cumulative incidence of prediabetes in Bogor was 50.3%. Factors associated with prediabetes were old age (RR: 1.33; 95% CI 1.19, 1.47), female gender (RR: 1.32; 95% CI 1.18, 1.48), overweight (RR: 1.17; 95% CI 1.01, 1.36), obesity (RR: 1.26; 95% CI 1.08, 1.46), central obesity (RR: 1.17; 95% CI 1.02, 1.34), high cholesterol levels (RR: 1.11; 95% CI 1.00, 1.22), and hypertension (RR: 1.27; 95% CI 1.14, 1.42). Conclusion: Age is a dominant risk factor for prediabetes. Therefore, it is important to stick to a healthy lifestyle by doing more physical activities and maintaining a balanced diet since young age to prevent prediabetes.
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Maghfiroh et al. (2024) conducted a cohort in Prediabetes. Old age was evaluated on Incidence of prediabetes (RR 1.33, 95% CI 1.19-1.47). Old age was a dominant risk factor for the incidence of prediabetes (RR 1.33; 95% CI 1.19-1.47), alongside female gender, obesity, high cholesterol, and hypertension.
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