Answers are grounded in this paper and cite their sources.
Seeing into cells: Genetically engineered, labeled ferritin is used to form biological nanoparticles displaying bait (B) and prey (P) molecules inside cells (see picture). Specific bait–prey interactions induce the interconnected assembly of nanoparticles into nanoclusters on a timescale of seconds. This phenotypic readout with a small molecule as an inducible switch was used to directly visualize dynamic molecular interactions within living cells.
No takes yet. Share an insight, caveat, or question.
Lee et al. (2011) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: