Why the study?
Redo aortic valve replacement carries an increased risk of patient-prosthesis mismatch, making it crucial to evaluate the safety of concomitant aortic root enlargement to guide patient selection.
Does concomitant aortic root enlargement reduce major adverse cardiovascular events in patients undergoing redo aortic valve replacement?
Does concomitant aortic root enlargement reduce major adverse cardiovascular events in patients undergoing redo aortic valve replacement?
Aortic root enlargement during redo aortic valve replacement is safe and not associated with increased perioperative mortality or morbidity, while improving hemodynamic parameters.
OBJECTIVES: Redo aortic valve replacement (AVR) might present an increased risk for predicted patient-prosthesis mismatch (PPM). Aortic root enlargement (ARE) procedures can decrease PPM and improve hemodynamic parameters. It is crucial to evaluate the safety of ARE in the context of redo AVR to allow better patient selection. METHODS: This is a matched case-control study of 125 patients who underwent a redo AVR between 1991 and 2016, 21 patients had a concomitant ARE procedure. Patients were matched for age, gender, presence of coronary artery disease, renal clearance, left ventricular ejection fraction, and body mass index. The primary outcome was the occurrence of major adverse cardiovascular events (MACE). Secondary outcomes were postoperative impact of the ARE procedures on echocardiographic measurements and survival. RESULTS: (pre = 0.9, post = 1.3; P < .01), with a reduction of maximum and mean transvalvular gradients of 26.6 mm Hg (pre = 56.8, post = 30.2; P < .01) and 17.1 mm Hg (pre = 31.9, post = 14.8; P < .01), respectively. Postoperatively, the occurrence of MACE was similar (ARE = 19%, no ARE = 14%; P = .68). Survival rates were similar (P = .29). CONCLUSIONS: For patients undergoing redo AVR, ARE is not associated with higher perioperative mortality and morbidity when compared with patients undergoing AVR without ARE. The fear of perioperative complications potentially associated with ARE should not be a prohibiting factor in symptomatic redo patients with small aortic annulus and predicted PPM.
No takes yet. Share an insight, caveat, or question.
Chauvette et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: