Altered profile of mRNA expression in atrioventricular node of streptozotocin-induced diabetic rats

Figures

• 

  Figure 1.. Dissection of the atrioventricular node junction in a typical control heart showing the location where tissue samples were collected. CT, crista terminalis; RA, right atrium; TV, tricuspid valve; RV, right ventricle; VS, ventricular septum; AS, atrial septum; CS, coronary sinus; SAN, sinoatrial node; AVN, atrioventricular node; Ao, Aorta.

• 

  Figure 2.. Expression of genes encoding various intercellular proteins. Data are mean ± SEM, n=6–8 samples from STZ and control rat each containing samples from 2 hearts.

• 

  Figure 3.. Expression of genes encoding various cell membrane transport proteins. Data are mean ± SEM, n=5–8 samples from STZ and control rat each containing samples from 2 hearts. *P<0.05, **P<0.01 vs. CON-AVN.

• 

  Figure 4.. Expression of genes encoding various intracellular Ca2+ transport and Ca2+ regulation proteins. Data are mean ± SEM, n=7–8 samples from STZ and control rat each containing samples from 2 hearts. *P<0.05, **P<0.01 vs. CON-AVN.

• 

  Figure 5.. Expression of genes encoding various hyperpolarization-activated cyclic-nucleotide-gated channels. Data are mean ± SEM, n=5–8 samples from STZ and control rat each containing samples from 2 hearts. *P<0.05 vs. CON-AVN.

• 

  Figure 6.. Expression of genes encoding various calcium channel proteins. Data are mean ± SEM, n=5–9 samples from STZ and control rat each containing samples from 2 hearts. **P<0.01 vs. CON-AVN.

• 

  Figure 7.. Expression of genes encoding various sodium channel proteins. Data are mean ± SEM, n=5–9 samples from STZ and control rat each containing samples from 2 hearts. *P<0.05, **P<0.01 vs. CON-AVN.

• 

  Figure 8.. (A and B) Expression of genes encoding various potassium channel proteins. Data are mean ± SEM, n=5–8 samples from STZ and control rat each containing samples from 2 hearts. *P<0.05, **P<0.01 vs. CON-AVN.

• 

  Figure 9.. Expression of genes encoding miscellaneous cardiac proteins. Data are mean ± SEM, n=6–8 samples from STZ and control rat each containing samples from 2 hearts. *P<0.05, **P<0.01 vs. CON-AVN.

• 

  Figure 10.. (A) Typical western blot comparing expression of various proteins from STZ and control AVN. β-actin which was used as the loading control is also shown in each blot. The blots shown are representative of 6 individual samples from STZ and control rats. (B) Protein/β-actin ratios for the different proteins. Data are mean ± SEM, n=6 samples from STZ and control rat each containing 3 pooled AVNs from a total of 18 hearts AVN. *P<0.05, **P<0.01 vs. CON-AVN.