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Narrative review reveals multimodal treatment approaches in gastric cancer ovarian metastasis, highlighting individualized surgery combined with chemotherapy to improve survival.
The incidence of gastric cancer is currently increasing, with gastrectomy and D2 Lymphadenectomy being the primary treatments for resectable gastric cancer. For advanced or unresectable metastatic gastric cancer, systemic treatment options include chemotherapy, targeted therapy, or immunotherapy. Krukenberg tumours are types of metastatic tumours in the ovaries that exclusively occur in female patients and that originate from the stomach. Previously deemed an incurable stage of advanced disease, the prognosis of patients with ovarian metastases from gastric cancer depends on multiple factors, including tumour biology and treatment response. With the development of comprehensive cancer treatment options, the combination of surgery and chemotherapy has gradually become the primary treatment for patients with ovarian metastasis from gastric cancer. Individualised comprehensive treatment regimens are crucial for improving patient outcomes. This review summarises the comprehensive treatment strategies for ovarian metastasis from gastric cancer.
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Wu et al. (2025) studied this question.
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