Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 2015Organic & Biomolecular Chemistry

Discovery of 4-acetyl-3-(4-fluorophenyl)-1-(p-tolyl)-5-methylpyrrole as a dual inhibitor of human P-glycoprotein and Staphylococcus aureus Nor A efflux pump

View Full Paper
Ask AI
Bookmark
Share

Authors

JBJaideep B. BharateUniversity of Arkansas for Medical SciencesSSSamsher SinghNanyang Technological UniversityAWAbubakar WaniSt. Jude Children's Research Hospital

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Bharate et al. (2015) studied this question.

synapsesocial.com/papers/6a7b54c602ab7a73dd034afdhttps://doi.org/10.1039/c5ob00246j
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Osthol and curcumin as inhibitors of human Pgp and multidrug efflux pumps of Staphylococcus aureus: reversing the resistance against frontline antibacterial drugs2014 · 62 citations
  2. 2Computational Models for Identifying Potential P-Glycoprotein Substrates and Inhibitors2005 · 115 citations
  3. 3New Is Old, and Old Is New: Recent Advances in Antibiotic-Based, Antibiotic-Free and Ethnomedical Treatments against Methicillin-Resistant Staphylococcus aureus Wound Infections2016 · 29 citations
  4. 4Lead Identification for Modulators of Multidrug Resistance based on in silico Screening with a Pharmacophoric Feature Model2004 · 62 citations
  5. 5Iron(III)-Catalyzed Four-Component Coupling Reaction of 1,3-Dicarbonyl Compounds, Amines, Aldehydes, and Nitroalkanes: A Simple and Direct Synthesis of Functionalized Pyrroles2010 · 269 citations