Key result
A larger pre-procedural angle between the interatrial septum and the left atrial appendage orifice was significantly associated with the presence of peri-device leakage (52.3° vs 41.9°, p=0.019).
Why the study?
Does pre-procedural 3D geometric CT analysis of the interatrial septum and LAA orifice predict peri-device leakage in patients undergoing LAA device closure?
Observational (n=22)
No
Does pre-procedural 3D geometric CT analysis of the interatrial septum and LAA orifice predict peri-device leakage in patients undergoing LAA device closure?
Absolute Event Rate: 52.3% vs 41.9%
p-value: p=0.019
Pre-procedural 3D CT geometric analysis of the angle between the interatrial septum and LAA orifice can help predict peri-device leakage after LAA closure, potentially guiding individualized procedural planning.
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May support pre-procedural CT planning in LAA closure; hypothesis-generating and requires prospective validation before practice change.
Chung et al. (2015) conducted an observational in Atrial fibrillation with high risk for stroke (n=22). Peri-device leakage vs. No peri-device leakage was evaluated on Pre-procedural angle θ between the interatrial septum plane and the line linking the LAA orifice center and foramen ovale (p=0.019). A larger pre-procedural angle between the interatrial septum and the left atrial appendage orifice was significantly associated with the presence of peri-device leakage (52.3° vs 41.9°, p=0.019).
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