Summary: YADA can deisotope and decharge high-resolution mass spectra from large peptide molecules, link the precursor monoisotopic peak information to the corresponding tandem mass spectrum, and account for different co-fragmenting ion species (multiplexed spectra). We describe how YADA enables a pipeline consisting of ProLuCID and DTASelect for analyzing large-scale middle-down proteomics data. Availability: http://fields.scripps.edu/yada Contact: paulo@pcarvalho.com Supplementary information: Supplementary data are available at Bioinformatics online.
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Carvalho et al. (2009) studied this question.
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