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June 30, 2014European Respiratory JournalOpen Access

Oxidative stress in cystic fibrosis lung disease: an early event, but worth targeting?

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Abstract

A recent study showed that oxidative stress occurs early in CF lung disease and represents a potential drug target http://ow.ly/vdH2P

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Cite This Study

Hector et al. (2014) studied this question.

synapsesocial.com/papers/6a7b64732eb3c7e469f44f22 https://doi.org/10.1183/09031936.00038114

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Glutathione aerosol suppresses lung epithelial surface inflammatory cell-derived oxidants in cystic fibrosisOriginal Research · 1999 · 114 citations
2Risk Factors for Bronchiectasis in Children with Cystic FibrosisCohort Study · 2013 · 605 citations
3High-dose oral <i>N</i> -acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosisEarly-Phase Clinical Trial · 2006 · 253 citations
4Abnormal glutathione transport in cystic fibrosis airway epitheliaOriginal Research · 1999 · 203 citations
5Identifying the Origins of Cystic Fibrosis Lung DiseaseOriginal Research · 2013 · 19 citations