We report stereoselective synthesis of bicyclo[3.2.1]oct-6-en-2-ones through Au(I)-catalyzed cycloisomerization of an allenene-acetal functionality. This cyclization is mechanistically significant because it involves an unprecedented 1,3-addition of a sp 3 -hybridized C−H bond to vinylcarbenoid moiety.
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Bhunia et al. (2008) studied this question.
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