January 1, 2003Circulation JournalOpen Access

Association of Body Mass Index, Body Fat, and Weight Gain With Inflammation Markers Among Rural Residents in Japan.

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Population

1,053 residents aged 40 years and older from a rural community in Japan, excluding those reporting a cold or who did not undergo blood examinations.

Outcome

Association of body mass index (BMI), body fat, and weight gain with inflammation markers (C-reactive protein, fibrinogen, serum albumin, and white blood cell count)surrogate

In a rural Japanese population, obesity and weight gain are significantly associated with elevated CRP levels, highlighting the role of adiposity in low-grade chronic inflammation.

Limitations

Combined data from males and females rather than using sex-specific data
CRP measurement was not a highly sensitive assay, underestimating the relationship for very low concentrations
High intra-individual variability of inflammation markers such as fibrinogen, serum albumin, and WBC
Other inflammatory diseases (e.g., rheumatoid arthritis) were not assessed

Discussion

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Implication

Supports adiposity-inflammation link in rural Japanese adults; hypothesis-generating and should not yet change practice.

Cite This Study

Saito et al. (2003) studied this question.

synapsesocial.com/papers/6a7b77a7fbd9051d3b0eb222 https://doi.org/10.1253/circj.67.323

Topics

Sermorelin

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Association of Body Mass Index, Body Fat, and Weight Gain With Inflammation Markers Among Rural Residents in Japan.

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Topics

Association of Body Mass Index, Body Fat, and Weight Gain With Inflammation Markers Among Rural Residents in Japan.

Structured PICO

Limitations

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider