Key result
Atrioventricular block was detected in 7% of emergency department patients >40 years old, with older age (OR 2.8), ischemic heart disease (OR 1.9), and diabetes (OR 3.9) as independent predictors.
Why the study?
In Syria, ongoing conflict has severely impacted healthcare infrastructure, potentially affecting the prevalence and management of atrioventricular block.
Cross-Sectional (n=692)
No
Odds Ratio: 2.8 (95% CI 1.6–5.6)
p-value: p=<0.001
Routine ECG screening in the ED identified a 7% prevalence of AVB among patients over 40 in a conflict-affected Syrian setting, strongly predicted by older age, ischemic heart disease, and diabetes.
May guide targeted ED ECG screening in high-risk patients; leaves open prospective validation of outcomes.
BACKGROUND: Atrioventricular block (AVB) is a cardiac conduction disorder that can lead to significant clinical outcomes, particularly in resource-limited and conflict-affected regions. In Syria, healthcare infrastructure has been severely impacted by ongoing conflict, potentially affecting the prevalence and management of AVB. METHODS: We conducted a cross-sectional study at Tishreen University Hospital in Latakia, Syria, with patients > 40 who presented to the emergency department (ED) from June 1 to August 1, 2024. Routine 12-lead ECGs were performed, with AVB diagnoses confirmed by two independent cardiology consultants. Exclusion criteria included pre-existing AVB, pacemaker presence, hemodynamic instability, and ECG diagnostic discrepancies. Patient demographics and comorbidities were assessed, and logistic regression analyses identified predictors of AVB. RESULTS: The final analysis included 692 patients, of which AVB was detected in 7% of the cohort. Patients with AVB were significantly older (median age 76 vs. 54 years, p < 0.001) and had higher rates of ischemic heart disease (IHD) (62% vs. 14%, p < 0.001) and diabetes (56% vs. 21%, p = 0.01). Logistic regression showed older age (odds ratio [OR]: 2.8, 95% confidence interval [CI]: 1.6-5.6, p < 0.001), IHD (OR: 1.9, 95% CI: 1.4-4.5, p < 0.001), and DM (OR: 3.9, 95% CI: 2.9-8.3, p < 0.001) were independently associated with AVB. CONCLUSION: AVB prevalence in the Syrian ED setting is high, with age, IHD, and diabetes as significant predictors. Routine ECG screening in EDs may facilitate early AVB detection in at-risk populations, especially in conflict-affected regions with limited healthcare resources. This approach could improve outcomes by enabling timely intervention in high-risk patients.
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Antoun et al. (2025) conducted a cross-sectional in Atrioventricular block (AVB) (n=692). Older age, ischemic heart disease, and diabetes was evaluated on Atrioventricular block (AVB) (OR 2.8, 95% CI 1.6-5.6, p=<0.001). Atrioventricular block was detected in 7% of emergency department patients >40 years old, with older age (OR 2.8), ischemic heart disease (OR 1.9), and diabetes (OR 3.9) as independent predictors.
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