Triton X-100 aqueous micelle accelerates the rate of Baylis–Hillman reaction and enhances the product yield. The type and concentration of surfactants play prominent roles in the reaction. An aqueous micelle Triton X-100 is easily recovered and reused for four runs without substantial loss in yield. 1,4-diazabicyclo[2.2.2]octane (DABCO) (20 mol%) is found to be a good basic catalyst in aqueous micelle. Apparently, this protocol has several advantages such as green reaction medium, mild reaction condition, ease of product recovery and moderate-to-good yield of product.
No takes yet. Share an insight, caveat, or question.
Pawar et al. (2011) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: