Why the study?
Does the 6MWT accurately reflect functional exercise capacity and correlate with clinical parameters in children with ESRD?
Population
20 children with end-stage renal disease on dialysis for more than 3 months.
Comparison
Six-minute walking test performance evaluation. vs Reference values obtained in healthy children.
Design
Cross-sectional
Key result
Children with end-stage renal disease showed a significantly reduced six-minute walking test performance, achieving only 83% of the predicted distance for healthy children (p<0.0001).
Authors
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Supports 6MWT for monitoring pediatric ESRD status; leaves open accuracy versus exercise testing and practice change.
Cross-Sectional (n=20)
Yes
Does the 6MWT accurately reflect functional exercise capacity and correlate with clinical parameters in children with ESRD?
Absolute Event Rate: 83% vs 100%
p-value: p=<0.0001
The 6MWT is a useful instrument for monitoring clinical status in children with ESRD, strongly associated with hematocrit and height, though it cannot substitute for progressive exercise testing.
Takken et al. (2009) conducted a cross-sectional in End-stage renal disease (ESRD) (n=20). End-stage renal disease vs. Healthy children (reference values) was evaluated on Six-minute walking test (6MWT) performance as a percentage of predicted reference values (p=<0.0001). Children with end-stage renal disease showed a significantly reduced six-minute walking test performance, achieving only 83% of the predicted distance for healthy children (p<0.0001).