Key result
Single-operator LAAO protocol achieves 100% same-day discharge and effective 1-year appendage closure.
Why the study?
Contemporary procedural guidelines for WATCHMAN LAAO require resource-intensive measures that are not economically feasible for many hospital systems, prompting evaluation of a more minimalistic implantation strategy.
Is a single-operator, TEE-guided, conscious sedation protocol without pre-imaging and with same-day discharge feasible and safe for LAAO?
Case Report (n=5)
Open-label
No
Is a single-operator, TEE-guided, conscious sedation protocol without pre-imaging and with same-day discharge feasible and safe for LAAO?
A minimalistic, single-operator approach to LAAO with conscious sedation and same-day discharge appears feasible and safe in a small case series.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for single-operator same-day LAAO; larger prospective trials needed before clinical adoption.
Background: Contemporary procedural guidelines for percutaneous left atrial appendage occlusions (LAAO) with the WATCHMAN device often require the utilization of pre-screening imaging, general anaesthesia, intubation, a dedicated intra-procedural echocardiographer, and overnight observation. For these reasons, LAAO with the WATCHMAN is not economically feasible for many hospital systems. Thus, we sought to evaluate a newstrategy for implantation that may provide a more minimalistic and less cumbersome approach to LAAO. Case summary: We describe five cases utilizing single-operator left atrial appendage occlusion utilizing conscious sedation, transoesophageal echocardiography, lack of outpatient pre-imaging, and same-day expedited discharge (SOLO-CLOSE)-a novel single-operator procedural strategy for LAAO that safely foregoes the aforementioned procedural requirements and allows for same-day early discharge. All five patients were observed according to our newly devised SOLO-CLOSE protocol and were safely discharged home the same day. Follow-up transoesophageal echocardiography (TEE) at 45 days and 1 year revealed well-seated and well-anchored devices with no leaks (<5 mm) or device-related thrombi. Discussion: The SOLO-CLOSE series is the first ever documented WATCHMAN strategy that utilizes a single-operator, TEE-guided, nurse-driven conscious sedation protocol that defers pre-screening imaging and allows for same-day discharge. The versatility of this technique allows proceduralists to comfortably achieve successful LAAO despite a wide range of risk profiles. This single-operator technique has potential to become a widely accepted universal approach for non-pharmacological cardioembolic stroke prophylaxis due to its efficacy, safety, simplicity, and presumable cost-effectiveness.
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Golzarian et al. (2023) conducted a case report in Non-valvular atrial fibrillation (n=5). SOLO-CLOSE strategy (single-operator LAAO with WATCHMAN FLX using conscious sedation, TEE, no outpatient pre-imaging, and same-day discharge) was evaluated on Successful left atrial appendage occlusion with same-day discharge and absence of peri-device leaks (<5 mm) or device-related thrombi at 45 days and 1 year. The SOLO-CLOSE single-operator LAAO strategy achieved 100% (5/5) same-day discharge and 100% effective appendage closure with no leaks (<5 mm) or thrombi at 45 days and 1 year.
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