Key result
In elderly patients with atrial fibrillation and gastrointestinal bleeding, chronic kidney disease was significantly associated with an increased risk of 30-day emergency department revisit for bleeding episodes (OR 5.74).
Why the study?
To evaluate the frequency of ED revisits among elderly patients with gastrointestinal bleeding secondary to anticoagulant treatment and identify factors associated with an increased risk of ED revisits.
What are the risk factors for 30-day emergency department revisit in elderly patients with atrial fibrillation and gastrointestinal bleeding secondary to anticoagulant therapy?
Cohort (n=80)
No
What are the risk factors for 30-day emergency department revisit in elderly patients with atrial fibrillation and gastrointestinal bleeding secondary to anticoagulant therapy?
Elderly patients with atrial fibrillation and gastrointestinal bleeding on anticoagulation have a 13.7% risk of 30-day ED revisit for bleeding, with chronic kidney disease being a significant risk factor.
Answers are grounded in this paper and cite their sources.
May support risk stratification for 30-day ED revisits after anticoagulant GI bleed in elderly AF; leaves open whether interventions alter outcomes.
OBJECTIVE: To evaluate the frequency of emergency department (ED) revisits among elderly patients with gastrointestinal bleeding secondary to anticoagulant treatment and identify factors associated with an increased risk of ED revisits. METHODS: A 3-year retrospective observational study was designed, including elderly patients (≥65 years) with atrial fibrillation and undergoing oral anticoagulation therapy who visited the ED for gastrointestinal bleeding. To evaluate the risk factors for 30-day revisit, a multivariate analysis was designed including comorbidities, concomitant treatment, change in anticoagulant treatment and prescription of direct-acting oral anticoagulants. RESULTS: 80 patients were included. At discharge, anticoagulation therapy was modified in 21 (26.2%) patients; and changed from an oral anticoagulant to heparin in 17 (21.2%) patients and to another oral anticoagulant in 4 (5.0%) patients. Anticoagulant treatment was withdrawn in 5 (6.3%) patients at discharge. Eleven (13.7%) patients revisited the ED 30 days after hospital discharge for bleeding episodes. No differences in the frequency of revisit to the ED were observed in the patients who changed their anticoagulant treatment at discharge. In the multivariate analysis, chronic kidney disease was the only factor significantly associated with revisits at 30 days. CONCLUSIONS: Elderly patients who experience a first episode of gastrointestinal bleeding have a high risk of revisiting the ED for a bleeding episode, with no particular differences between the types of anticoagulant prescribed at discharge.
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Ramos et al. (2020) conducted a cohort in Atrial fibrillation and gastrointestinal bleeding secondary to anticoagulant therapy (n=80). Chronic kidney disease vs. No chronic kidney disease was evaluated on 30-day emergency department revisit due to bleeding episode (OR 5.74, 95% CI 1.09-19.02, p=0.032). In elderly patients with atrial fibrillation and gastrointestinal bleeding, chronic kidney disease was significantly associated with an increased risk of 30-day emergency department revisit for bleeding episodes (OR 5.74).
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