Virus Activation by Host Proteinases. A Pivotal Role in the Spread of Infection, Tissue Tropism and Pathogenicity

Microbiology and ImmunologyVolume 39, Issue 1 p. 1-9 ReviewFree Access Virus Activation by Host Proteinases. A Pivotal Role in the Spread of Infection, Tissue Tropism and Pathogenicity Yoshiyuki Nagai, Yoshiyuki Nagai Department of Viral Infection, Institute of Medical Science, University of Tokyo, Shirokanedai 4-6-1, Minato-ku, Tokyo, 108 JapanSearch for more papers by this author Yoshiyuki Nagai, Yoshiyuki Nagai Department of Viral Infection, Institute of Medical Science, University of Tokyo, Shirokanedai 4-6-1, Minato-ku, Tokyo, 108 JapanSearch for more papers by this author First published: January 1995 https://doi.org/10.1111/j.1348-0421.1995.tb02161.xCitations: 35AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abbreviations FX blood clotting factor X HIV-1 human immunodeficiency virus type 1 NDV Newcastle disease virus PC proprotein convertase PIV3 parainfluenza virus 3 RSV respiratory syncytial virus VAP virus-activating proteinase. References 1Akaike, T., Molla, A., Ando, M., Araki, S., and Maeda, H. 1989. Molecular mechanism of complex infection by bacteria and virus analyzed by a model using serratial proteinase and influenza virus in mice. J. Virol. 63: 2252– 2259. CASPubMedWeb of Science®Google Scholar 2Barr, P.J. 1991. Mammalian subtilisins: the long-sought dibasic processing endoproteases. Cell 66: 1– 3. CrossrefCASPubMedWeb of Science®Google Scholar 3Blandford, G. 1975. Studies on the immune response and pathogenesis of Sendai virus infection of mice. III. The effects of cyclophosphamide. Immunology 28: 871– 883. CASPubMedWeb of Science®Google Scholar 4Bosch, V., and Pawlita, M. 1990. 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