What question did this study set out to answer?

Identify clinical and angiographic variables predictive of major adverse cardiac events following NIR stent placement in patients with coronary artery disease.

February 1, 2002Journal of Interventional Cardiology

Predictors of Clinical Outcome Following NIR Stent Implantation for Coronary Artery Disease: Analysis of the Results of the First International New Intravascular Rigid‐Flex Endovascular Stent Study (FINESS Trial)

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Why the study?

What are the predictors of adverse clinical outcomes following NIR stent implantation in patients with coronary artery disease?

Population

255 patients with coronary artery disease enrolled prospectively in a multicenter registry undergoing NIR…

Design

Cohort

Follow-up

6 months

Authors

SFSteven FeldRutgers, The State University of New Jersey YAYaron AlmagorInterventional / Structural Cardiology WVWilliam K. VaughnUniversity of Hawaiʻi at Mānoa

Discussion

Member takes

Implication

May support minimizing stent length in high-risk patients; hypothesis-generating and requires validation in contemporary randomized trials.

Key Points

Identify clinical and angiographic variables predictive of major adverse cardiac events following NIR stent placement in patients with coronary artery disease.
Analyzed prospective multicenter registry data from 255 patients (341 lesions) enrolled with broad entry criteria who underwent attempted NIR stent implantation between December 1995 and March 1996.
Performed stepwise logistic regression analysis on baseline clinical and angiographic features to determine independent predictors of outcomes during 6-month follow-up.
Multivessel disease, diabetes, and total length of the stented segment were independent predictors of major adverse cardiac events at 6-month follow-up.
Each 1 mm increase in stented segment length increased the risk for the combined endpoint of death or myocardial infarction by 3%.
Lesion length was not predictive of adverse clinical events on multivariate analysis.

Structured PICO

What are the predictors of adverse clinical outcomes following NIR stent implantation in patients with coronary artery disease?

Population

255 patients (341 lesions) with coronary artery disease enrolled prospectively in a multicenter registry undergoing NIR stent implantation

Intervention

NIR stent implantation

Outcome

Major adverse cardiac events (MACE) and combined end point of death or myocardial infarction at 6-month follow-upcomposite

Multivessel disease, diabetes, and longer stent length are predictors of adverse clinical outcomes following NIR stent implantation, suggesting that minimizing stent length to cover only significant stenoses may improve outcomes.

Cite This Study

Feld et al. (2002) studied this question.

synapsesocial.com/papers/6a7bde1301db1a7270ed2f08 https://doi.org/10.1111/j.1540-8183.2002.tb01025.x

Topics

Coronary artery disease

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Implication

May support minimizing stent length in high-risk patients; hypothesis-generating and requires validation in contemporary randomized trials.

Predictors of Clinical Outcome Following NIR Stent Implantation for Coronary Artery Disease: Analysis of the Results of the First International New Intravascular Rigid‐Flex Endovascular Stent Study (FINESS Trial)

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Predictors of Clinical Outcome Following NIR Stent Implantation for Coronary Artery Disease: Analysis of the Results of the First International New Intravascular Rigid‐Flex Endovascular Stent Study (FINESS Trial)

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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