Key result
Current evidence supports thromboprophylaxis for high-risk fractures such as hip, pelvic, and periarticular knee fractures, but routine prophylaxis is not justified for most isolated foot and ankle injuries.
Why the study?
Diagnosis, prophylaxis, and management of venous thromboembolism in patients with fractures remain highly controversial with little consensus in clinical practice or the literature.
What is the current evidence and consensus for thromboprophylaxis to prevent VTE in patients with various types of fractures?
What is the current evidence and consensus for thromboprophylaxis to prevent VTE in patients with various types of fractures?
This symposium summary highlights the ongoing controversy and lack of consensus regarding VTE prophylaxis in patients with various orthopedic fractures.
Variable VTE prophylaxis persists across fracture types; prospective trials needed to resolve ongoing debates.
Diagnosis, prophylaxis, and management of venous thromboembolism (VTE) in patients with fractures remain a highly controversial topic with little consensus in clinical practice or the literature. The following manuscript represents a summary of evidence presented at the 2017 OTA Annual Meeting Symposium; "Thromboprophylaxis an Update of Current Practice: Can We Reach A Consensus?" The need for prophylaxis in pelvic and acetabular fracture patients; the existing body of evidence related to VTE, pulmonary embolism (PE), and prophylaxis for patients with fractures about the knee; current evidence in Edinburgh Scotland, regarding VTE prophylaxis in patients with isolated ankle fractures and the risk of VTE in patients with a hip fracture are topics that are addressed. The reader will benefit from the wisdom of this compilation of global contributions on thromboprophylaxis.
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Ricci et al. (2019) conducted a review in Fractures (pelvic, acetabular, knee, foot/ankle, hip) and risk of venous thromboembolism. Thromboprophylaxis (chemical and mechanical) vs. No prophylaxis or alternative prophylaxis was evaluated on Venous thromboembolism (VTE) and pulmonary embolism (PE). Current evidence supports thromboprophylaxis for high-risk fractures such as hip, pelvic, and periarticular knee fractures, but routine prophylaxis is not justified for most isolated foot and ankle injuries.
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