Some Characteristics of the Hypothalamic “Drinking Centre” in the Goat as Shown by the Use of Permanent Electrodes

The response to electrical stimulation of the “drinking centre” was studied in one goat for a period of six months. Emotional factors and hydration were found to increase the stimulus threshold for drinking. Drinking continued for different lengths of time after cessation of stimulation. The after‐effect which may be due to an after‐discharge in the stimulated area of the hypothalamus was inhibited by the previous injection of amphetamine or the drinking of cold water. On repeated stimulations the animal learned to overcome a simple obstacle in order to gain access to the drinking water. If the goat was not allowed to drink, the stimulations elicited a typical “displacement reaction”. Prolonged strong stimulations of the “drinking centre” were not observed to alter the electrolyte metabolism significantly.