Sensitization experiments with textile dyes in guinea pigs

Experimental sensitization of guinea pigs with 6 azo and anthraquinone dyes used frequently as disperse dyes for fabrics (stockings, pantyhose) revealed that the blue dyes were moderate sensitizers while the red, yellow and orange dyes were only weak ones. This was found to be in contrast with the order based on the frequency of observed allergic sensitization, which showed the yellow and orange dyes at the top of the list and the blue dyes at the bottom.