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August 12, 2026CureusOpen Access

Clinico-Epidemiological Profile of Leptospirosis Among Patients Attending a Tertiary Care Center in Rajasthan

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Authors

RSRajesh SharmaSGSakshee GuptaMSMegha Sharma

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Overview

Cross-sectional study assesses seropositivity and epidemiology of leptospirosis in Rajasthan, highlighting risk factors.

Key Points

  • This study assesses the seropositivity for Leptospira and studies the clinico-epidemiological profile in patients at a tertiary care center in Rajasthan.
  • Cross-sectional study conducted from July 2019 to June 2022
  • 2,996 patients with undifferentiated febrile illness tested for Leptospira IgM antibodies by ELISA
  • 290 patients tested for Leptospira using PCR within five days of illness onset.
  • Seropositivity for Leptospira was 5.01% (150/2,996), with a male predominance (58.67%)
  • PCR testing showed no positive results (all negative from 290 samples)
  • Highest IgM positivity was noted in ages 19-30 years and during the monsoon and post-monsoon seasons, particularly in December (10.70%).

Cite This Study

Sharma et al. (2026) studied this question.

synapsesocial.com/papers/6a7c208206a85aed514b739fhttps://doi.org/10.7759/cureus.114221
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