Lipohypertrophy in Young Patients With Type 1 Diabetes

Abnormal injection sites may complicate insulin treatment in type 1 diabetic patients, leading to delayed insulin absorption (1). The aim of this study was to document the prevalence of lipohypertrophy in young patients treated with modern insulin regimens and devices and to assess parameters influencing its development. The injection sites of 282 children and adolescents (160 boys and 122 girls, median age 12.3 years [range 2.1–23.8]) with diabetes (duration 3.7 years [0.1–18.8]) were prospectively evaluated during outpatient clinic visits between 1 January and 31 March 2001. Findings were graded as followed: grade 0=no changes; grade …