It is still not known how deviations in the chromosomal constitution in man influence the fetal and postnatal development processes. More knowledge about the clinical variability between individuals and the degree of instability in different organ systems in human chromosomal syndromes would be of value. For many reasons, mongolism is one of the best syndromes for such investigations. The present paper reports on the variability and instability in newborn and older mongoloids, some of whom are part of a follow‐up study.
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Hall et al. (1972) studied this question.
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