Population
40 isolated, normal functioning mitral Hancock valves
Design
Cohort
Authors
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Hancock valve EOA assessment requires flow-specific references; leaves open whether current thresholds warrant guideline revision.
The effective orifice area of mitral Hancock xenograft valves is flow-dependent and consistently smaller than the theoretical area, suggesting that specific nomograms are needed to accurately assess valve function over time.
Ubago et al. (1980) studied this question.
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