Key result
Type 2 diabetes mellitus was associated with significantly lower adiponectin levels (2.5 vs 16 μg/mL; P<0.0001) and altered pro-inflammatory cytokine profiles compared to healthy controls.
Why the study?
Are serum levels of adiponectin and pro-inflammatory cytokines altered in Vietnamese patients with type 2 diabetes mellitus compared to healthy controls?
Population
130 Vietnamese individuals, comprising 73 patients with type 2 diabetes mellitus and 57 healthy controls…
Design
Case-control
Authors
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Does not support practice change; extends adiponectin findings to Vietnamese T2DM but leaves causality and utility open.
Case-Control (n=130)
Are serum levels of adiponectin and pro-inflammatory cytokines altered in Vietnamese patients with type 2 diabetes mellitus compared to healthy controls?
Absolute Event Rate: 2.5% vs 16%
p-value: p=< 0.0001
In Vietnamese patients with type 2 diabetes mellitus, adiponectin levels are significantly decreased and pro-inflammatory cytokines are altered, correlating with insulin resistance.
Tong et al. (2016) conducted a case-control in type 2 diabetes mellitus (n=130). Type 2 diabetes mellitus vs. Healthy controls was evaluated on Adiponectin levels (μg/mL) (p=< 0.0001). Type 2 diabetes mellitus was associated with significantly lower adiponectin levels (2.5 vs 16 μg/mL; P<0.0001) and altered pro-inflammatory cytokine profiles compared to healthy controls.
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