Determinants of Hypertension Among Patients with Diabetes mellitus in Public Hospitals of Kembata Tambaro Zone, South Nations Nationalities and Peoples Region, Ethiopia, 2021; A Case Control Study

Q: What is the clinical evidence from this study?

Study design: Case-Control. Population: Diabetes mellitus and hypertension comorbidity (n=326). Intervention: Physical inactivity (sedentary lifestyle), age ≥50 years, alcohol consumption, and poor diabetes knowledge vs. Physically active, age 18-30 years, no alcohol history, and good diabetes knowledge. Primary outcome: Hypertension (SBP ≥140 mmHg and/or DBP ≥90 mmHg or on regular antihypertensive therapy) among patients with diabetes mellitus (AOR 5.84, 95% CI 2.47-13.81, p=<0.05).

Q: What does this research mean for the field?

Age of 50 years or older, physical inactivity, alcohol consumption history, and poor diabetes knowledge significantly increase the odds of developing hypertension among patients with diabetes mellitus. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

Yeshialem Kenore; Solomon Abrha; Amanuel Yosef Gebrekidan; Temesgen Bati Gelgelu

doi:10.2147/jmdh.s379293

September 1, 2022Journal of Multidisciplinary HealthcareOpen Access

Determinants of Hypertension Among Patients with Diabetes mellitus in Public Hospitals of Kembata Tambaro Zone, South Nations Nationalities and Peoples Region, Ethiopia, 2021; A Case Control Study

View Full Paper

Ask AI

Bookmark

Share

Key result

Physical inactivity (AOR 5.84, 95% CI 2.47-13.81), age ≥50 years (AOR 7.00), poor diabetes knowledge (AOR 3.04), and alcohol intake (AOR 2.61) increased odds of hypertension in diabetic patients.

Why the study?

The comorbidity of hypertension and diabetes mellitus carries high complication risks, but data on determinants of hypertension among diabetic patients in Ethiopia are limited.

What socio-demographic, lifestyle, clinical, and knowledge-related factors are associated with the development of hypertension among patients with diabetes mellitus in public hospitals of Kambata Tambaro Zone, Ethiopia?

Key Points

To identify determinants of hypertension among patients with diabetes mellitus receiving care at public hospitals in the Kambata Tambaro Zone, Ethiopia.
Hospital-based unmatched case-control study conducted across five public hospitals involving 326 patients with diabetes (163 hypertensive cases and 163 normotensive controls) from June 17, 2021, to August 17, 2021.
Bivariable and multivariable binary logistic regression analyses were performed to identify factors independently associated with hypertension.
Age ≥50 years was significantly associated with hypertension compared to age 18–30 years (AOR = 7.00, 95% CI = 1.69–28.9).
Physical inactivity (AOR = 5.84, 95% CI = 2.47–13.81) and history of alcohol consumption (AOR = 2.61, 95% CI = 1.35–5.03) significantly increased the odds of hypertension.
Patients with poor knowledge regarding diabetes had greater odds of developing hypertension than those with good knowledge (AOR = 3.04, 95% CI = 1.69–5.47).

Study Design

Type

Case-Control (n=326)

Multicenter

Yes

Structured PICO

What socio-demographic, lifestyle, clinical, and knowledge-related factors are associated with the development of hypertension among patients with diabetes mellitus in public hospitals of Kambata Tambaro Zone, Ethiopia?

P

Population

326 adults aged ≥18 years with diabetes mellitus (40.2% female; 163 cases with hypertension and 163 controls without hypertension) on outpatient chronic care follow-up for at least 6 months across five public hospitals in Ethiopia.

E

Exposure

Exposure to risk determinants for hypertension including age ≥50 years, physical inactivity (<30 min/day for <5 days/week), history of alcohol drinking, and poor knowledge of diabetes (score <11.8 on 9-item tool)

C

Comparator

Unexposed reference groups among diabetic patients (age 18–30 years, physically active ≥30 min/day for ≥5 days/week, no history of alcohol drinking, and good knowledge of diabetes)

O

Outcome

Presence of hypertension among patients with diabetes mellitus, defined as mean SBP/DBP ≥140/90 mmHg confirmed by two measures taken at least 5 minutes apart, or being on regular drug therapy or follow-up for hypertensionsurrogate

Main Result

Odds Ratio: 5.84 (95% CI 2.47–13.81)

Absolute Event Rate: 93.9% vs 69.9%

p-value: p=<0.05

Limitations

Potential social desirability bias on sensitive self-reported variables such as current alcohol intake and smoking status
Factors requiring laboratory investigation, such as lipid profiles, were not included in the study
Social desirability bias on sensitive self-reported variables such as current alcohol intake and current smoking status
Laboratory investigations such as lipid profiles were not included in the study

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Identifies modifiable lifestyle and educational determinants—specifically physical inactivity, alcohol consumption, and poor diabetes knowledge—strongly associated with comorbid hypertension among patients with diabetes in Ethiopian public hospitals.

Abstract

Introduction: Hypertension is commonly defined as a persistently raised blood pressure in which systolic blood pressure reading (SBP) is greater than or equal to 140 mmHg and diastolic blood pressure (DBP) is greater than or equal to 90 mmHg. The comorbidity of hypertension and diabetes mellitus is complex and is associated with a high risk of complications. However, there are limited studies on determinants of hypertension among patients with diabetes in Ethiopia. Therefore this study aimed to identify the determinants of hypertension among patients with diabetes mellitus in public hospitals of the Kambata Tambaro Zone, Ethiopia. Methods and Materials: A hospital-based unmatched case-control study was conducted among a total sample of 326 patients with diabetes from June 17, 2021 to August 17, 2021. This study was conducted in five public hospitals. The data were entered into EpiData version 3.1 software and exported to and analyzed using SPSS software version 25.0. Bivariable and multivariable binary logistic regression analyses were used to determine the association between the dependent and independent variables. Results: Of the 336 study participants, 326 diabetic patients (163 cases and 163 controls) were interviewed resulting in a response rate of 97%. Age group ≥50 years (Adjusted Odds Ratio = 7.00, 95% CI = 1.69-28.9), inactivity in physical exercise (AOR = 5.84, 95% CI = 2.47-13.81), patients who have a history of drinking alcohol (AOR = 2.61, 95% CI = 1.35-5.03) and patients who had poor knowledge on diabetes (AOR = 3.04, 95% CI = 1.69-5.47) were more likely to develop hypertension among diabetic patients. Conclusion: This study concluded that age, inactivity in physical exercise, history of alcohol intake and poor knowledge were determinants of hypertension among diabetic patients.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Kenore et al. (2022) conducted a case-control in Diabetes mellitus and hypertension comorbidity (n=326). Physical inactivity (sedentary lifestyle), age ≥50 years, alcohol consumption, and poor diabetes knowledge vs. Physically active, age 18-30 years, no alcohol history, and good diabetes knowledge was evaluated on Hypertension (SBP ≥140 mmHg and/or DBP ≥90 mmHg or on regular antihypertensive therapy) among patients with diabetes mellitus (AOR 5.84, 95% CI 2.47-13.81, p=<0.05). Physical inactivity (AOR 5.84, 95% CI 2.47-13.81), age ≥50 years (AOR 7.00), poor diabetes knowledge (AOR 3.04), and alcohol intake (AOR 2.61) increased odds of hypertension in diabetic patients.

synapsesocial.com/papers/6a7c7b973f411608c626c895 https://doi.org/10.2147/jmdh.s379293

View Full Paper

Ask AI

Bookmark

Share

Determinants of Hypertension Among Patients with Diabetes mellitus in Public Hospitals of Kembata Tambaro Zone, South Nations Nationalities and Peoples Region, Ethiopia, 2021; A Case Control Study

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Determinants of Hypertension Among Patients with Diabetes mellitus in Public Hospitals of Kembata Tambaro Zone, South Nations Nationalities and Peoples Region, Ethiopia, 2021; A Case Control Study

Key Points

Study Design

Structured PICO

Main Result

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading