Stoichiometric reduction of artemisinin to dihydroartemisinin (DHA) has been successfully transferred from batch to continuous flow conditions with a significant increase in productivity and an increase in selectivity. The DHA space-time-yield of up to 1.6 kg h –1 L –1 was attained which represents a 42 times increase in throughput compared to that of conventional batch process.
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Fan et al. (2012) studied this question.
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