A 53-year-old woman presented with insidiously progressive tetraparesis, C5 sensitive level and urinary incontinence for 16 months. Cervical MRI disclosed signal abnormalities consistent with subacute combined degeneration 1 (SCD), associated with a hydromyelia (figure). Laboratory studies confirmed the diagnosis of SCD. Clinical and imagiologic remission occurred with vitamin B12 treatment.
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Canas et al. (2005) studied this question.