Key result
Simple inflammatory markers obtained from whole blood count analysis, such as NLR, MLR, PLR, SII, SIRI, and AISI, serve as inexpensive and easily available predictors of worse long-term outcomes following off-pump coronary artery bypass surgery.
Why the study?
To review the current knowledge regarding the clinical utility and prognostic significance of simple inflammatory markers in off pump surgery.
Do simple inflammatory markers predict long-term survival in patients undergoing off-pump coronary artery bypass surgery?
Do simple inflammatory markers predict long-term survival in patients undergoing off-pump coronary artery bypass surgery?
Simple, inexpensive inflammatory markers from whole blood counts may help risk-stratify patients undergoing off-pump coronary artery bypass surgery for worse long-term outcomes.
The inflammatory background of coronary artery disease is gaining more attention in recent times. Off pump surgery is minimally invasive type of surgical revascularization with relatively low number of applications in cardiac surgery centers worldwide that allows for perioperative inflammatory reactions minimalization. The simple inflammatory markers (neutrophil to lymphocyte ratio (NLR), monocyte to lymphocyte ratio (MLR), platelets to lymphocyte ratio (PLR), systemic inflammatory index (SII), systemic inflammatory response index (SIRI), aggregate index of systemic inflammation (AISI)) possess a clinically significant impact on patients' prognosis and may help to improve patients' long-term results. The review presents the current knowledge regarding their utility in clinical practice. Assessment of inflammatory indices obtained from whole blood count analysis allows to indicate those patients who need scrupulous follow-up due to predicted worse long-term survival. Perioperative measurement and analysis of simple whole blood counts is inexpensive and easily available and may improve the results of surgical revascularization by better identification of patients at higher risk of worse outcomes.
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Urbanowicz et al. (2022) conducted a review in Coronary artery disease undergoing off-pump coronary artery bypass surgery (OPCAB). Simple inflammatory markers (NLR, MLR, PLR, SII, SIRI, AISI) was evaluated. Simple inflammatory markers obtained from whole blood count analysis, such as NLR, MLR, PLR, SII, SIRI, and AISI, serve as inexpensive and easily available predictors of worse long-term outcomes following off-pump coronary artery bypass surgery.
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