The effects of isopropyl N-(3-chlorophenyl) carbamate (CIPC) on Vicia faba root tip cells were studied. The contraction of mitotic chromosomes was conspicuously intensified by CIPC. The susceptibility to CIPC was comparatively lower in this plant than in other reported plants regarding to a growth inhibition, and the degree of contraction of chromosomes was rather time dependent but not very significantly dose dependent. Regular formation of mitotic apparatus was blocked. Autoradiography showed the depression of RNA synthesis in nucleus.
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Yoshida et al. (1983) studied this question.
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