Why the study?
Does off-pump CABG alter postoperative cardiac autonomic regulation and ventricular repolarization in patients undergoing elective revascularization?
Population
42 patients electively admitted for off-pump CABG, mean age 61.9 +/- 9.3 years, mean EURO score 2.6 +/- 1.9.
Comparison
Off-pump coronary artery bypass grafting (CABG) vs Preoperative baseline (within-subject comparison)
Design
Cohort
Follow-up
4 weeks
Authors
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Post-op QT variability and impaired QT-RR coupling may signal arrhythmic vulnerability after off-pump CABG; leaves open whether these changes predict events or warrant monitoring.
Does off-pump CABG alter postoperative cardiac autonomic regulation and ventricular repolarization in patients undergoing elective revascularization?
Off-pump CABG leads to profound autonomic derangement and loss of rate-dependent regulation (QT-RR coupling) that persists up to 4 weeks postoperatively, potentially promoting arrhythmias.
Kališnik et al. (2006) studied this question.
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