Key result
Targeting inflammation, lipid dysfunction, and hypertension offers potential targets for novel cardiovascular therapies.
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Atherosclerosis-related cardiovascular disease is one of the leading causes of death in China [1]. With advances in our understanding of the molecular mechanisms of atherosclerosis vascular inflammation, lipid metabolism dysfunction, and hypertension are regarded as the main pathogenetic pathways of both early atherogenesis and advanced plaque rupture [2,3]. Currently, much attention is being paid to the control of these pathways, which offers the potential for development of novel therapeutic approaches in the treatment of cardiovascular disease in China.
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Yin et al. (2011) conducted a review in Atherosclerosis-related cardiovascular disease. Vascular inflammation, lipid metabolism dysfunction, and hypertension pathways was evaluated. Controlling vascular inflammation, lipid metabolism dysfunction, and hypertension offers potential for novel cardiovascular therapies in China, though no quantitative data are reported.
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