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June 9, 2010Clinical Cancer Research

Targeting Notch to Target Cancer Stem Cells

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Authors

APAntonio PannutiIstituto Nazionale Biostrutture e BiosistemiKFKimberly E. ForemanLoyola University Medical CenterPRPaola RizzoUniversity of Ferrara

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Pannuti et al. (2010) studied this question.

synapsesocial.com/papers/6a7cb3a1b7ca9b673b7cd2f4https://doi.org/10.1158/1078-0432.ccr-09-2823
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Notch Activation Induces Akt Signaling via an Autocrine Loop to Prevent Apoptosis in Breast Epithelial Cells2009 · 171 citations
  2. 2Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway2009 · 623 citations