Cap‐Assisted Synthesis of Hetero‐Trifunctional Cyclodextrins, from Flamingo Cap to Bascule Bridge

This microreview focuses on the use of cyclodextrin‐capping for the selective synthesis of cyclodextrins bearing three different functionalities. Three strategies have been employed and are discussed: dissymmetrical capping, regioselective opening of a symmetrical cap, and the more efficient cap‐oriented regioselective deprotection. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)