The impact of HMG-CoA reductase inhibition on the incidence and severity of graft-versus-host disease in patients with acute leukemia undergoing allogeneic transplantation

To the editor: Acute graft-versus-host disease (GVHD) is the major cause of morbidity and mortality after allogeneic stem-cell transplantation (SCT).[1][1] In the December 15, 2007, issue of Blood , Zeiser and colleagues[2][2] reported protective effects of atorvastatin against acute GVHD in a