A preliminary study of approaches for extracting and analyzing data from particle holograms concludes that (1 ) for "thin" spherical particles, out-of-focus methods are optimum; (2) for "thin" nonspherical particles, out-of-focus methods are useful but must be supplemented by in-focus methods; and (3) a complex method of projection and back-projection can remove the unwanted out-of-focus data for "deep" particles.
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H. John Caulfield (1985) studied this question.