Key result
Adults 80 and older show a ~38% decline in stroke incidence alongside falling dementia rates.
Observational
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INTRODUCTION: We discovered a concomitant decline in stroke and dementia incidence rates at a whole population level in Ontario, Canada. This study explores these trends within demographic subgroups. METHODS: We analyzed administrative data sources using validated algorithms to calculate stroke and dementia incidence rates from 2002 to 2013. RESULTS: For more than 12 years, stroke incidence remained unchanged among those aged 20 to 49 years and decreased for those aged 50 to 64, 65 to 79, and 80+ years by 22.7%, 36.9%, and 37.9%, respectively. Dementia incidence increased by 17.3% and 23.5% in those aged 20 to 49 and 50 to 64 years, respectively, remained unchanged in those aged 65 to 79 years, and decreased by 15.4% in those aged 80+ years. DISCUSSION: The concomitant decline in stroke and dementia incidence rates may depict how successful stroke prevention has targeted shared risk factors of both conditions, especially at advanced ages where such risk factors are highly prevalent. We lend support for the development of an integrated system of stroke and dementia prevention.
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Cerasuolo et al. (2017) conducted an observational in Stroke and dementia. Age and sex subgroups over calendar time (2002-2013) vs. Baseline calendar period and younger age strata was evaluated on Stroke and dementia incidence rate trends. Adults aged 80+ years experienced a 37.9% decline in stroke incidence and a 15.4% decline in dementia incidence from 2002 to 2013, while dementia rose in those aged 20-64.
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