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November 1, 1980Proceedings of the National Academy of SciencesOpen Access

Proportion of hemoglobin G Philadelphia (alpha 268 Asn leads to Lys beta 2) in heterozygotes is determined by alpha-globin gene deletions.

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Authors

GSGwendolyn B. SancarUniversity of North Carolina at Chapel HillBTB TatsisMCMarisol CedenoState University of New York

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Sancar et al. (1980) studied this question.

synapsesocial.com/papers/6a7cc58cf40403d04c3f7558https://doi.org/10.1073/pnas.77.11.6874
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Triplicated alpha-globin loci in humans.1980 · 240 citations
  2. 2Differences between - and -Chain Mutants of Human Haemoglobin and between - and -Thalassaemia. Possible Duplication of the -Chain Gene1968 · 113 citations
  3. 3Thalassemia Syndromes1966 · 99 citations