Heavy Atom Isotope Effects Reveal a Highly Polarized Transition State for Chorismate Mutase

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTHeavy Atom Isotope Effects Reveal a Highly Polarized Transition State for Chorismate MutaseDarin J. Gustin, Patrizio Mattei, Peter Kast, Olaf Wiest, Lac Lee, W. Wallace Cleland, and Donald HilvertView Author Information Department of Chemistry, The Scripps Research Institute La Jolla, California, 92037 Laboratorium für Organische Chemie Swiss Federal Institute of Technology (ETH) Universitätstrasse 16, CH-8092 Zürich, Switzerland Department of Chemistry and Biochemistry University of Notre Dame, Notre Dame, Indiana 46556-5670 Institute for Enzyme Research and Department of Biochemistry University of Wisconsin, 1710 University Avenue Madison, Wisconsin 53705 Cite this: J. Am. Chem. Soc. 1999, 121, 8, 1756–1757Publication Date (Web):February 11, 1999Publication History Received3 December 1998Published online11 February 1999Published inissue 1 March 1999https://pubs.acs.org/doi/10.1021/ja9841759https://doi.org/10.1021/ja9841759rapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views506Altmetric-Citations74LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Chemical structure,Isotope effects,Isotopes,Peptides and proteins,Transition states Get e-Alerts