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cillin penetrates the growing cell more readily than the 'washed resting' cell. It would, however, seem equally possible that the loss of ability to oxidize guanylic acid following growth in the presence of penicillin is a secondary effect following some primary disorganization, an explanation put forward to explain the somewhat similar results obtained for the effect of penicillin on glutamnic acid accumulation (Gale & Rodwell, 1949).
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Kenten et al. (1953) studied this question.
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