Why the study?
Does moderate-to-high-intensity aerobic exercise improve cerebral blood flow in patients with mild to moderate Alzheimer's disease?
Does moderate-to-high-intensity aerobic exercise improve cerebral blood flow in patients with mild to moderate Alzheimer's disease?
A 16-week moderate-to-high-intensity aerobic exercise program does not significantly increase cerebral blood flow in patients with mild to moderate Alzheimer's disease.
Answers are grounded in this paper and cite their sources.
Exercise does not augment cerebral blood flow in mild-moderate Alzheimer's; challenges vascular hypotheses and redirects trials to non-perfusion mechanisms.
In recent years there has been an increasing focus on the relation between cerebrovascular health, physical exercise and Alzheimer's disease. The aim of the current study was to determine the effect of moderate-to-high-intensity aerobic exercise on cerebral blood flow in patients with mild to moderate Alzheimer's disease. Fifty-one patients were randomized to either usual care or moderate-to-high intensity aerobic exercise for 16 weeks. Exercise had no consistent effect on whole brain or regional cerebral blood flow. Sixteen weeks of exercise are, therefore, not sufficient to produce a consistent increase in cerebral blood flow in a relatively small sample of Alzheimer's patients.
No takes yet. Share an insight, caveat, or question.
Kleij et al. (2018) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: