Why the study?
Mediastinal biopsies carry risks of high-risk complications like cardiac tissue damage and decompensation, requiring interventional radiologists to anticipate and be prepared to manage life-threatening cardiac complications.
Interventional radiologists performing mediastinal biopsies should be prepared to emergently manage iatrogenic cardiac tamponade using percutaneous pericardial drainage.
Low complication rates in CT-guided biopsies support procedural safety; leaves open need for prospective validation before practice change.
Computed tomography guided biopsies are common interventional procedures that are necessary for confirmation of imaging findings. Additionally, percutaneous biopsies are necessary for the elucidation of a patient's clinical findings with disease pathology. Though interventionists perform these procedures regularly without consequence, various complications may arise depending on the tissues biopsied. Examples of such complications may include hemorrhage, hematoma formation, or perforation of surrounding vessels. In the case of mediastinal biopsies, less common but higher-risk complications may include pneumothorax, perforation of arterial vessels, and damage to the cardiac tissues resulting in decompensation. Interventionists should understand the risks of performing these procedures and should be prepared to intervene if life-threatening complications arise. As interventional cardiologists are often prepared to manage decompensating cardiac complications, interventional radiologists must likewise anticipate the same to occur when conducting procedures that may affect cardiac tissues. The following case demonstrates a technique for correcting a complicated complication arising from a mediastinal biopsy, which resulted in a pericardial effusion and patient decompensation.
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Harmon et al. (2018) studied this question.
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